Center of research excellence for Systems Pharmacology

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Research interest

          Systems Pharmacology is a new discipline that is gaining attentions in the international research community. Focusing on quantitative reasoning and the investigation of drug mechanisms from the cellular level upto the population level, Systems Pharmacology helps advance drug discovery and development in a network-centric fashion. Realizing the potentials of this new research paradigm, the Faculty of Medicine Siriraj Hospital, as a leading medical research institute in Thailand, has launched a new research program called the Siriraj Initiative in Systems Pharmacology (SiSP) in 2015 to fulfill this research need. Led by two young pioneers, Dr.Somponnat Sampattavanich and Dr.Siwanon Jirawatnotai both ex-Bostonian researchers, SiSP is designed from its start to be a multidisciplinary, collaborative and resourceful incubator for talented Thai scientists. SiSP has three major missions,

  1. to improve the quality of Thai public healthcare via systems-based investigation.
  2. to create omics database that can lay down foundation for heterogeneous drug response in Thai populations.
  3. to advance technology for improving drug discovery and development.


Publication

จำนวนผลงานตีพิมพ์ทั้งหมด : 373 รายการ แสดง 5 รายการ

Jareemit N, Therasakvichya S, Freitas F, Paiva G, Ramírez LAC, Berkowitz RS, Horowitz NS, Maestá I, Fülöp V, Braga A, Elias KM. .
 EMACO for treatment of gestational trophoblastic neoplasia: A multinational multicenter study .
Journal Name :  Gynecologic Oncology.  2023.  170  114-122.
Department : Obstetrics and Gynaecology
Source : Scopus

Niyomnaitham S., Jongkaewwattana A., Meesing A., Pinpathomrat N., Nanthapisal S., Hirankarn N., Siwamogsatham S., Kirdlarp S., Chaiwarith R., Lawpoolsri S., Phanthanawiboon S., Thitithanyanont A., Hansasuta P., Chaiyaroj S., Pitisuttithum P. .
 Immunogenicity of a fractional or full third dose of AZD1222 vaccine or BNT162b2 messenger RNA vaccine after two doses of CoronaVac vaccines against the Delta and Omicron variants .
Journal Name :  International Journal of Infectious Diseases.  2023.  129  19-31.
Department : Pharmacology
Source : Scopus

Krittiyanitsakun S, Nampoolsuksan C, Tawantanakorn T, Suwatthanarak T, Srisuworanan N, Taweerutchana V, Parakonthun T, Phalanusitthepha C, Swangsri J, Akaraviputh T, Methasate A, Chinswangwatanakul V, Trakarnsanga A. .
 Is fascial closure required for a 12-mm trocar? A comparative study on trocar site hernia with long-term follow up .
Journal Name :  World Journal of Clinical Cases.  2023.  11  (2): 357-365.
Department : Surgery
Source : Scopus

Prasopporn S., Suppramote O., Ponvilawan B., Jamyuang C., Chanthercrob J., Chaiboonchoe A., More-Krong P., Kongsri K., Suntiparpluacha M., Chanwat R., Korphaisarn K., Okada S., Sampattavanich S., Jirawatnotai S. .
 Corrigendum: Combining the SMAC mimetic LCL161 with Gemcitabine plus Cisplatin therapy inhibits and prevents the emergence of multidrug resistance in cholangiocarcinoma(Front. Oncol., (2022), 12, (1021632), 10.3389/fonc.2022.1021632) .
Journal Name :  Frontiers in Oncology.  2023.  12 
Department : Medicine/Pharmacology/Siriraj Center of Research Excellence for Precision Medicine and Systems Pharmacology
Source : Scopus

Niyomnaitham S., Atakulreka S., Wongprompitak P., Copeland K.K., Toh Z.Q., Licciardi P.V., Srisutthisamphan K., Jansarikit L., Chokephaibulkit K. .
 Immunogenicity and reactogenicity of accelerated regimens of fractional intradermal COVID-19 vaccinations .
Journal Name :  Frontiers in Immunology.  2023.  13 
Department : Pediatrics/Pharmacology/Immunology/ฝ่ายวิจัย
Source : Scopus

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