Body Mass Index Combined with Possible Sarcopenia Status Is Better Than BMI or Possible Sarcopenia Status Alone for Predicting All-Cause Mortality Among Asian Community-Dwelling Older Adults.
Chalermsri, C., W. Aekplakorn and V. Srinonprasert. 2022.
Frontiers in Nutrition. 9:881121.
Background: Body mass index (BMI) and sarcopenia are common indicators of
nutritional status. Possible sarcopenia, defined as low muscle strength or performance,
was recently introduced by the Asian Working Group for Sarcopenia (AWGS) in 2019. We
investigated for association between all-cause mortality and BMI combined with possible
sarcopenia severity in Asian older adults.
Methods: This study included a subpopulation (8,195 participants aged ≥60 years;
male gender: 49.4%; mean age: 69.2 ± 6.8 years) from the Fourth Thai National Health
Examination Survey (NHES-IV). BMI was classified using Asia-Pacific cut-offs. Possible
sarcopenia was defined using quadriceps strength based on AWGS 2019 criteria, and
possible sarcopenia severity was determined using study population quartile cut-offs.
All-cause mortality data was derived from the national vital registry in 2020.
Results: The prevalence of underweight status and possible sarcopenia was 11.8 and
38.9%, respectively. Multivariate analysis showed underweight individuals with severe
possible sarcopenia to be at highest risk for increased mortality [adjusted hazard ratio
(aHR): 3.98, 95% confidence interval (CI): 2.89–5.48], and higher risk was found in men
compared to women (aHR: 5.35, 95% CI: 1.19–8.97). Obese status without possible
sarcopenia was an independent protective factor (aHR: 0.61, 95% CI: 0.38–0.97).
Conclusion: BMI combined with possible sarcopenia severity is a better predictor of
mortality risk than either parameter alone.
Keywords:bodymassindex,BMI,possiblesarcopeniastatus,all causemortality,Asiancommunity-dwellingolder adults
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